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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
POU1F1
All Species:
38.18
Human Site:
S222
Identified Species:
64.62
UniProt:
P28069
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P28069
NP_000297.1
291
32912
S222
R
K
R
R
T
T
I
S
I
A
A
K
D
A
L
Chimpanzee
Pan troglodytes
XP_526244
291
32921
S222
R
K
R
R
T
T
I
S
I
A
A
K
D
A
L
Rhesus Macaque
Macaca mulatta
Q28503
291
32940
S222
R
K
R
R
T
T
I
S
I
A
A
K
D
A
L
Dog
Lupus familis
XP_549108
361
39472
S284
R
K
R
K
K
R
T
S
I
E
V
S
V
K
G
Cat
Felis silvestris
Mouse
Mus musculus
Q00286
291
32867
S222
R
K
R
R
T
T
I
S
V
A
A
K
D
A
L
Rat
Rattus norvegicus
P10037
291
32885
S222
R
K
R
R
T
T
I
S
I
A
A
K
D
A
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001515178
338
38300
S268
R
K
R
R
T
T
I
S
I
A
A
K
E
A
L
Chicken
Gallus gallus
Q9YGL7
363
40431
S293
R
K
R
R
T
T
I
S
I
S
A
K
E
A
L
Frog
Xenopus laevis
P31363
375
41827
S292
R
K
R
K
K
R
T
S
I
E
V
G
V
K
G
Zebra Danio
Brachydanio rerio
P79745
443
47434
S336
R
K
R
K
K
R
T
S
I
E
V
S
V
K
G
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P16241
427
45909
S310
R
K
R
K
K
R
T
S
I
E
V
S
V
K
G
Honey Bee
Apis mellifera
XP_393686
460
49306
S347
R
K
R
K
K
R
T
S
I
E
V
S
V
K
G
Nematode Worm
Caenorhab. elegans
P20268
380
42556
R285
A
G
R
K
R
K
K
R
T
S
I
E
V
N
V
Sea Urchin
Strong. purpuratus
XP_782909
467
49786
S317
R
K
R
K
K
R
T
S
I
E
V
T
I
K
G
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.6
98.9
35.1
N.A.
95.5
95.8
N.A.
66.2
70.2
34.9
30.2
N.A.
31.3
30.2
34.2
29.5
Protein Similarity:
100
100
98.9
48.7
N.A.
97.9
97.9
N.A.
73
75.7
50.4
44.9
N.A.
45.4
43.9
46.3
41.5
P-Site Identity:
100
100
100
33.3
N.A.
93.3
100
N.A.
93.3
86.6
33.3
33.3
N.A.
33.3
33.3
6.6
33.3
P-Site Similarity:
100
100
100
40
N.A.
100
100
N.A.
100
100
40
40
N.A.
40
40
33.3
40
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
0
0
0
0
0
0
0
0
43
50
0
0
50
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
36
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
43
0
8
15
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
8
0
0
0
0
0
0
0
0
0
8
0
0
43
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
50
0
86
0
8
0
8
0
0
% I
% Lys:
0
93
0
50
43
8
8
0
0
0
0
50
0
43
0
% K
% Leu:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
50
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
8
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
93
0
100
50
8
43
0
8
0
0
0
0
0
0
0
% R
% Ser:
0
0
0
0
0
0
0
93
0
15
0
29
0
0
0
% S
% Thr:
0
0
0
0
50
50
43
0
8
0
0
8
0
0
0
% T
% Val:
0
0
0
0
0
0
0
0
8
0
43
0
43
0
8
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _